Balsamiq Mockups

Using Balsamiq Mockups feels like you are drawing, but its digital, so you can tweak and rearrange controls easily, and the end result is much cleaner.

Commercial Mac OS X Windows Web

Axure RP

Axure RP is the leading tool for rapidly creating wireframes, prototypes and specifications for applications and web sites.

Commercial Mac OS X Windows

Adobe Experience Design CC

"Go from idea to prototype faster with Experience Design CC (Beta), the first all-in-one cross-platform tool for designing and prototyping websites and mobile apps....

Commercial Mac OS X Windows