MATLAB

MATLAB is a numerical computing environment and programming language.

Commercial Mac OS X Windows Linux

R (programming language)

R is a free software environment for statistical computing and graphics.

Free Open Source Mac OS X Windows Linux BSD

Mathematica

Mathematica is a computational software program used widely in scientific, engineering, and mathematical fields and other areas of technical computing.

Commercial Mac OS X Windows Linux Web

Sage

Sage is a free open-source mathematics software system licensed under the GPL. It combines the power of many existing open-source packages into a common Python-based interface.

Free Open Source Mac OS X Windows Linux Web

wxMaxima

wxMaxima is a document based interface for the computer algebra system Maxima. wxMaxima uses wxWidgets and runs natively on Windows, X11 and Mac OS X.

Free Open Source Mac OS X Windows Linux

Maple

Maple is a general-purpose commercial computer algebra system. Users can enter mathematics in traditional mathematical notation. Custom user interfaces can also be created.

Commercial Mac OS X Windows Linux

SymPy

SymPy is a Python library for symbolic computation. The stated goals of the library are to become a full-featured computer algebra system and to keep a simple code base to promote extensibility and comprehensibility.

Free Open Source Mac OS X Windows Linux

Derive

Derive 6.1: Powerful system for doing symbolic and numeric mathematics. This application is no longer available or supported.

Commercial Windows